Ultimate Guide to the Top Focus Supplements in 2023

The significance of cognitive function and focus in our daily life is undeniable. As we age, however, we inevitably face the challenge of cognitive decline. This has led to a heightened interest in methods to enhance our mental abilities.

One such method includes focus supplements, which have gained recognition for their potential to combat cognitive decline and improve concentration. In this article, we’ll explore these brain supplements in detail, providing valuable information to assist you in making informed decisions about your brain health.

Understanding Cognitive Function

Cognitive function refers to our brain’s ability to process information, remember things, solve problems, and focus or concentrate on tasks. It’s what allows us to perform everyday activities efficiently. However, factors like age, stress, lack of sleep, poor nutrition, and certain health conditions can negatively affect cognitive function, leading to a decline in our ability to focus and remember things.

Common Causes of Cognitive Decline

Several factors can cause cognitive decline. Age is a major one, as our brains naturally change over time. Chronic conditions like diabetes, high blood pressure, and obesity can also contribute to cognitive decline. Mental health issues such as depression and chronic stress play a role too. Other causes include lack of physical activity, sleep disorders like sleep apnea, and certain medications. It’s important to note that while these factors increase the risk, they don’t guarantee cognitive decline will occur.

How Focus Supplements Improve Cognitive Function

Focus supplements are designed to enhance the health of brain cells & support healthy cognitive function. They can boost memory, attention, and problem-solving skills. They work by providing essential nutrients and compounds for healthy brain function. The science behind brain health supplements lies in their unique ingredients.

These could include omega-3 fatty acids, known for their brain health benefits, or B vitamins that slow cognitive decline. Some focus supplements contain nootropics specifically designed to boost cognitive performance. By supplying the brain with these key components, focus supplements aim to improve concentration and mental clarity, helping us perform at our best.

Essential Focus Supplements for Cognitive Enhancement

The following research-backed supplements have been shown to improve focus, memory and concentration:


Based on data from a 20-year prospective cohort study, it was discovered that consuming more magnesium is linked to improved sleep quality and a lower likelihood of getting less than 7 hours of sleep. [1] Additionally, there is some indication that magnesium may be beneficial for children with ADHD, as ADHD could potentially be connected to a lack of magnesium. [2]

Omega-3 fatty acids

Omega-3s are crucial for brain development and cardiovascular well-being as they possess anti-inflammatory properties. In healthy older individuals, consuming a higher dosage (900 mg) of DHA may offer some benefits in delaying cognitive decline. [3]

B Vitamins

Certain B vitamins, such as folate, vitamin B6, and B12, can potentially slow cognitive decline in people without dementia. However, the impact is minimal and not completely proven, but studies conducted over a year have shown promising outcomes. Furthermore, folate has also been associated with a decreased likelihood of developing dementia. [4]


Blueberries are beneficial to maintain brain health, support heart health, and protect the liver. Blueberries’ high levels of antioxidants and anthocyanins help combat cognitive decline and reduce fat buildup in the liver. Research has shown that blueberries can improve brain health in individuals with cognitive decline and may offer potential benefits for young, healthy individuals based on animal studies. [5][6]


Caffeine, a nootropic, enhances cognitive function by stimulating neurons and improving reaction time. It also boosts alertness and has been found in clinical research to have the potential to prevent Alzheimer’s disease. [7][8]


Taking L-theanine as a supplement can boost cognitive function, especially when paired with caffeine. Combining these two supplements enhances cognitive function because it reduces the over-excitability caused by caffeine without reducing its stimulating effect, ultimately improving focus and attention span. [9]

Gingko Biloba

Ginkgo biloba has been found to enhance cognitive functions in individuals with dementia [10]. Furthermore, it offers cognitive performance advantages for healthy middle-aged and older individuals. [11][12]

Rhodiola Rosea

Rhodiola Rosea, an adaptogenic herb, enhances mental performance and reduces brain fog, fatigue, and stress. Its effects are especially notable in high-pressure situations. [13]

Bacopa Monnieri

Bacopa monnieri is a powerful herb known for its use in traditional medicine to boost cognitive function and promote longevity. Research indicates that it can potentially improve various types of memory, with a special focus on working memory. This means it can benefit both healthy individuals and those facing cognitive decline. [14]


Phosphatidylserine (PS) is a substance that supports cognitive function and is derived from amino acids in the brain. Fish is a great source of PS and has been linked to better memory and lower cortisol levels in older individuals. Studies suggest that taking daily phosphatidylserine supplements within the 15-50mg/kg range can help mitigate cognitive decline in aging rats. [15]

Lion’s Mane Mushroom

Research has shown that Lion’s Mane Mushroom may help prevent cognitive decline in rats caused by β-amyloid pigmentation. In humans, taking a 3g dose of 98% Lion’s Mane powder in capsule form has been linked to improved dementia rating scales, potentially enhancing overall cognitive health. [16]


Taking cholinergic can increase the levels of acetylcholine in the brain, leading to improved muscle strength, enhanced reflexes, and potentially an increased ability to learn.

Lifestyle Changes to Support Cognitive Health

Maintaining cognitive health goes beyond just taking dietary supplements. It involves adopting a lifestyle to support brain health. First, a diet rich in fruits, vegetables, lean protein, and healthy fats can provide the nutrients necessary for optimal brain function. Regular physical exercise keeps the body fit and enhances brain health by improving blood flow.

Managing stress through mindfulness practices like meditation or yoga can help maintain a healthy brain by reducing harmful inflammation. Lastly, getting adequate sleep is crucial as it allows the brain to rest, repair, and consolidate memories, contributing to improved cognitive function.

Frequently Asked Questions about Focus Supplements

Q: Are focus supplements safe for long-term use?

A: Safety varies by supplement and individual health. Always consult a healthcare professional.

Q: How long does it take for focus supplements to show results?

A: Results can vary; some may notice changes in a few days, others may need several weeks.

Q: Are there any potential side effects of focus supplements?

A: Side effects depend on the supplement. Common ones include digestive upset, headaches, or insomnia. Always start with a low dose and consult a healthcare professional.

Tips for Choosing and Using Focus Supplements

When choosing and using focus supplements, evaluating the product’s quality and reliability is crucial. Look for supplements that third-party labs have tested for purity and potency. Consult with healthcare professionals before starting any new supplement regimen to ensure it’s safe and suitable for your needs. They can also guide you on the proper dosage and usage guidelines.

Once you start taking the dietary supplement, monitor its effects closely. Note any changes in your focus, memory, overall cognitive function, and side effects. This will help you assess the supplement’s effectiveness and adjust your dosage if necessary. Always remember that supplements should be part of a holistic approach to cognitive health, including a balanced diet, regular physical activity, stress management, and adequate sleep.


In conclusion, maintaining optimal cognitive function is essential for everyday tasks, decision-making, and overall quality of life. Exploring focus supplements can be a beneficial step toward enhancing cognitive abilities, but it’s important to remember that they are not a standalone solution.

True brain health necessitates a comprehensive approach, balancing a nutritious diet, regular physical activity, stress management, sleep hygiene, and responsible supplement use. This holistic approach can help ensure your brain remains sharp and agile, paving the way for improved focus, memory, and cognitive longevity.


[1] Zhang Y, Chen C, Lu L, Knutson KL, Carnethon MR, Fly AD, Luo J, Haas DM, Shikany JM, Kahe K. Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study. Sleep. 2022 Apr 11;45(4):zsab276. doi: 10.1093/sleep/zsab276. PMID: 34883514; PMCID: PMC8996025.

[2] Kozielec T, Starobrat-Hermelin B. Assessment of magnesium levels in children with attention deficit hyperactivity disorder (ADHD). Magnes Res. 1997 Jun;10(2):143-8. PMID: 9368235.

[3] Yurko-Mauro K, McCarthy D, Rom D, Nelson EB, Ryan AS, Blackwell A, Salem N Jr, Stedman M; MIDAS Investigators. Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline. Alzheimers Dement. 2010 Nov;6(6):456-64. doi: 10.1016/j.jalz.2010.01.013. PMID: 20434961.

[4] Wang Z, Zhu W, Xing Y, Jia J, Tang Y. B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis. Nutr Rev. 2022 Mar 10;80(4):931-949. doi: 10.1093/nutrit/nuab057. PMID: 34432056.

[5] Hein S, Whyte AR, Wood E, Rodriguez-Mateos A, Williams CM. Systematic Review of the Effects of Blueberry on Cognitive Performance as We Age. J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):984-995. doi: 10.1093/gerona/glz082. PMID: 30941401.

[6] Krikorian R, Shidler MD, Nash TA, Kalt W, Vinqvist-Tymchuk MR, Shukitt-Hale B, Joseph JA. Blueberry supplementation improves memory in older adults. J Agric Food Chem. 2010 Apr 14;58(7):3996-4000. doi: 10.1021/jf9029332. PMID: 20047325; PMCID: PMC2850944.

[7] Adan A, Serra-Grabulosa JM. Effects of caffeine and glucose, alone and combined, on cognitive performance. Hum Psychopharmacol. 2010 Jun-Jul;25(4):310-7. doi: 10.1002/hup.1115. PMID: 20521321.

[8] Childs E, de Wit H. Subjective, behavioral, and physiological effects of acute caffeine in light, nondependent caffeine users. Psychopharmacology (Berl). 2006 May;185(4):514-23. doi: 10.1007/s00213-006-0341-3. Epub 2006 Mar 16. PMID: 16541243.

[9] Owen GN, Parnell H, De Bruin EA, Rycroft JA. The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci. 2008 Aug;11(4):193-8. doi: 10.1179/147683008X301513. PMID: 18681988.

[10] Hashiguchi M, Ohta Y, Shimizu M, Maruyama J, Mochizuki M. Meta-analysis of the efficacy and safety of Ginkgo biloba extract for the treatment of dementia. J Pharm Health Care Sci. 2015 Apr 10;1:14. doi: 10.1186/s40780-015-0014-7. PMID: 26819725; PMCID: PMC4729005.

[11] Kaschel R. Specific memory effects of Ginkgo biloba extract EGb 761 in middle-aged healthy volunteers. Phytomedicine. 2011 Nov 15;18(14):1202-7. doi: 10.1016/j.phymed.2011.06.021. Epub 2011 Jul 30. PMID: 21802920.

[12] Mix JA, Crews WD Jr. A double-blind, placebo-controlled, randomized trial of Ginkgo biloba extract EGb 761 in a sample of cognitively intact older adults: neuropsychological findings. Hum Psychopharmacol. 2002 Aug;17(6):267-77. doi: 10.1002/hup.412. PMID: 12404671.

[13] Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine. 2000 Apr;7(2):85-9. doi: 10.1016/S0944-7113(00)80078-1. PMID: 10839209.

[14] Calabrese C, Gregory WL, Leo M, Kraemer D, Bone K, Oken B. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. J Altern Complement Med. 2008 Jul;14(6):707-13. doi: 10.1089/acm.2008.0018. PMID: 18611150; PMCID: PMC3153866.

[15] Calderini G, Aporti F, Bellini F, Bonetti AC, Teolato S, Zanotti A, Toffano G. Pharmacological effect of phosphatidylserine on age-dependent memory dysfunction. Ann N Y Acad Sci. 1985;444:504-6. doi: 10.1111/j.1749-6632.1985.tb37626.x. PMID: 3860111.

[16] Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009 Mar;23(3):367-72. doi: 10.1002/ptr.2634. PMID: 18844328.

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Dr. Linnea Passaler

Dr. Linnea Passaler

Dr. Linnea Passaler has dedicated 20+ years to serving patients, first to a small number of individuals as a successful surgeon and then to thousands of people worldwide as the CEO of a digital health startup. After overcoming her own struggles with a dysregulated nervous system, she created Heal Your Nervous System (HYNS) to empower others in their healing journey. Her combination of neuroscience and somatic work helps those struggling with overwhelm, trauma, burnout, and anxiety to heal their dysregulated nervous systems and thrive.